知
·
識
·
饗
·
宴
KNOWLEDGE
FEAST SERIES
216
Y
d࿁ΌਿΪ͟
LA
ٙʱؓ
ܝ
dҬՑ
SLC1A3
glial high-
affinity glutamate transporter, member 3
ਿΪf
Ң
ࡁ
ٙΥЪ٫࿁
SLC1A3
ਿΪ
ܘ
ชጳሳdႩ
މ
̴࿁
MS
षᜊዚՓɰϞᗫd͟ኅᶶაձ˂
ژ
̆ᶶაޫ
މ
ՈՐዧ
ٙग़ෂኬ
ي
ሯ
neurotransmitter
dϾ
SLC1A3
ঐਗ਼
ኅᶶაձ˂
ژ
̆ᶶა
ߤ
༁ࠦՑ̮ࠦfટഹ˼
ࡁ
ఱί
SLC1A3
ਿΪ
ڐڝ
ЪਿΪۨᛡй
genotyping
ڋ
ӉҬՑɓ
ࡈ
ఊࣨ
苷
აεۨ
SNP
ਿΪᅺাၾ
MS
፲
ෂϞᗫfࣛ
͟Ӻ༟๕Ϟࠢd
ה
˸̥͜༰ˇ
MS
षԷᐏഐ
؈
d
ܝ
Ը
ί
2007
ϋdอ
ߵ
ࣸᚆᔼኪᕏႦ
The New England Journal of
Medicine
,
NEJM
̈ତəɓ
ࡈ
˖¨
Risk alleles for multiple
sclerosis identified by a genomewide study
©̴݊ɓ
੬ڢࡈ
ɽ
ۨٙӺ
ࠇ
dЇˇ͜ə
1
ຬε
ࡈ
ྼ᜕࿁̘ਂΌਿΪଡ଼ᗫ
ᑌӺ
GWAS
dϾ˲݊༨ٙΥЪdϤ
ࠇ
ྌҬՑ௰ࠠ
ࠅ
ٙ
2
ࡈ
ਿΪၾ
MS
Ϟᗫdɓ
ࡈ
݊
IL2R
d̤̮ɓ
ࡈ
݊
IL7R
f
ҢՑ
IL7R
ਿΪλ྅Чಀᗆdԫྼɪ
IL7R
ਿΪɰ̙л
͜
LA
ҬՑdԨ˲
IL7R
ఱί
SLC1A3
ڐڝ
d൷ᕎʔՑ
1
ࡈ
Mb
mega base pairs
f
ഐႧ
Liquid association
݊ɓ
ࡈ
ʱؓ͛
ي
༟ࣘٙც
ࠅ
Ͼ
೯
̈Ըٙ୕
ࠇ
ᝈׂd
LA
݊ʔ̙݊˸͜ίՉ˼ٙή˙kҢ
ڦ
ഈࣩ݊
ٵ
֛ٙf༊ซdҢ
ࡁ
ձʾٙᗫ
ڷ
dϞࣛ
ࡉ
ᗫ
ܘڷ
λఱ྅͍݊Σ
positive
d̙݊Ыːઋʔλٙ
