中草藥與新藥研發
239
CRF
fᐖसषɛᎇषઋٙ೯࢝dˈՉʷᐕ
ܝ
ึԻ೯ೌ
ܨج
ూ˲ଢ଼ጐϓᘌࠠٙहसdұጋषɛЇϥɳf
PG2 injection
ତʊᓒɽЇʕࠬ
ط
ᐕdͦ
ۃ
ʕᔼᖹɽኪආБᑗґ༊᜕
ʕྡɞf
2.
රᨾಷ
රᨾಷ݊ɽ
ߒ
1800
ϋ
ۃ
уʊᄿԴ͜ʘʕᖹ˙ኒd
̴݊ɓ֭ձ༆ኒďঐᆠ˟лdձʕ˟೨f͟රᨾe͚
ণeԇᖹeɽಈ
4
၇
ʕᖹ
ה
ଡ଼ϓf˙ʕරᨾdᆠ˟лd
ग़༵͉ণፗՉ˴໑⮗
೧د
dԇᖹձᐄ˟೨dग़༵͉
රᨾಷ
(
Huang Chin Tang):
ձ༆ኒ
–
̌ঐᆠ˟лdձʕ˟೨
µ
රᨾ
Scutellaria baicalensis
͚ণ
Glycyrrhiza uralensis
µ
ԇᖹ
Paeonia lactiflora
ɽಈ
Ziziphus jujuba
µ
ෆఫሞj˴
ط
˄ජˇජΥषdԒᆠɹ߮d໖೨ɨлd
೧א
श໖೨ϞᆠdЉ
߸ߎ
රdএָᅰഃस
µ
ಷ᎘ဂ
–
රᨾԇণၾɽಈdɨл໖೨㛪ᆠ
µ
PHY906
̙͜˸д
Irinotecan
ط
ᐕഐٜ໑ᐖ
ה
ˏৎٙ
ߗ
ᖹձᘌࠠ໖ᓧ
Ƕ
Topotecin
(
Hycamptin)
Ƕ
Irinotecan (Camptosar)
Ƕ
amptothecin
ఃዓ
HO
NMe
2
O
O
O
CO N
O
O
HO
N N
HCI
HCI
N N O
O
O
HO
N
N O
O
O
HO
圖九：黃芩湯的研發與應用（
Saif MW & Cheng YC et al,
Phytomedicine
,
2010, 17, 161
）
治療對於
fluorouracil
無效
的轉移性結腸癌
治療晚期卵巢癌
