知
·
識
·
饗
·
宴
KNOWLEDGE
FEAST SERIES
212
arginine
dவც
ࠅ
ཀɓஹЕٙʷኪˀᏐdϾӊɓӉ
ʷኪˀᏐேଘऒՑɓ
ࡈ
९fˀᏐ௰
ڋ
ٙ๕᎘݊ኅᶶა
glutamate
කdཀɔ。ᇅᶶაΥϓ
酶
ARG2
dટ
ഹΎ
ࡈ
ˀᏐdᔷᜊϓᶶა
ornithine
ආɝ҇९ృᐑ
ਸ਼fɨɓӉdᶶა
ࠅ
Աҏᜊϓ͘ᶶა
citrulline
dၚऄ
ਿ
ޝ
ა
L-arginino-succinate
d௰
ܝ
ʑՑၚᶶაdϾ
圖二：尿素循環
(
Li, K.C. (2002) Genome-wide co-expression dynamics: theory and
application.
Proceedings of National Academy of Science
. 99, 16875-16880.)
ARG4
ARG1
ARG3
CARI
aspartate
citrulline
ornithine
urea
Proline
L-glutamate-5-semialdehyde
carbamoyl
phosphate
N-acetyl-
glutamate
Glutamine
Glutamate
arginine
L-arginino-
succinate
ARG2
CPA2
CPA1
CAR2
Figure 2: The four genes in the urea cycle are coded by ARG3, ARG1, ARG4, and
CAR1 in S. Cerevisiae.
ARG2 encodes acetyl-glutamate synthase, which catalyzes the first step
of ornithine biosynthesis. CPA1 and CPA2 encode small and large units of
carbamoylphossphate synthetase. CAR2 encodes ornithine aminotransferase. This
chart is adapted from KEGG.
fumarate
