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€ Proceedings of the National Academy of Sciences of the
United States of America, PNASd೯ڌəவɓᇐ¨ Genome-
wide coexpression dynamics: Theory and application© ˖௝d
ֵɨఱԸሔሔவᇐ˖௝ٙ౻ߠf
ʔΝਿΪගٙʝਗᗫ ڷ݊ਿΪ᜗޼Ӻٙɓ ࡈ˴ൿf຅
2ࡈਿΪί΢၇ઋرɨڌତඎٙᜊਗϞ৷ܘ޴Ч೻ ܓࣛd͛
يኪ࢕ ࡁึႩ މ̴ࡁ ί̌ঐɪɰ̙ঐ݊ᗳЧא ึϞ޴ᗫf
޴ᗫڷᅰ݊˾ ڌ 2ࡈਿΪග ڌ ତඎ৷ЭϞεɓ ߧٙ੬͜୕
ࠇඎf ה ˸຅ҢࡁϞə n˪ Microarray಻੻୚ߤ ίnࡈ ઋر
€condition ɨpࡈ ਿΪٙڌତඎ ܝd̙ᄳϓɓ ࡈॉ৬€p
rows, n columnsi
X11 X12 nn X1n
X21 X22 nn X2n
nn
nn
Xp1 Xp2 nn Xpn
Ң ࡁ̙̘ၑrowၾrowගٙ޴ᗫڷᅰdආϾҪ޴ᗫڷᅰ
༰৷ٙ row ኋඎરίɓৎdவఱ݊clusteringf͛ي ኪ࢕ࡁ
̙˸ܘ࢙׸ٙ޶̈ɓࡈcluster㛪εᅰਿΪ΍Νٙ̌ঐdආϾ
ɽᑔήཫ಻ίΝɓcluster㛪Չ˼͊ٝਿΪɰึϞ޴ᗫ̌ঐf
͛ي ኪ࢕̙˸ટɨ̘ணࠇ ྼ᜕᜕ᗇ৿ணfШҢତί ࠅˀཀ
Ըਪd຅2ࡈ ਿΪʊٝϞ޴ᗫٙ̌ঐdԟ˼ࡁ ίਿΪ ڌତ